During our recent lighting workshop we shot manual, metered everything, and used artificial lighting; a lot of work to get set. But once set up, Alan encouraged use to change it up; come in close. back off, change angle and perspective, and of course change the models pose. As a result, once the initial work is done building a scene and lighting, you get a lot of variety of shots from one setup.
As simple and sensible as this sounds I had a tendency to take a few shots and then modify the lighting or change the position of the set requiring new significant time and effort. I needed to constantly remind myself to thoroughly work a set before moving on.
This image uses a single medium sized softbox on the left elevated above the model's head.